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 B​RAIN MAPPING

Q & A with Prof William Seeley: OHBM 2016 Keynote Speaker Series

7/28/2016

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BY NILS MUHLERT & JESSICA TURNER
Professor William Seeley is a neurologist and principal investigator at the Memory and Aging Centre in UC San Francisco. There, William (Bill) leads the selective vulnerability lab. His team combines neuroimaging with neuropathological experiments, to map the neural networks affected by disease and uncover the drivers of those network-level changes. Bill’s keynote speech focussed on ‘Network-based neurodegeneration’ – here we find out more about Bill’s background and the challenges of this converging macro- and micro-level approach.

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Keep Calm and Scan On

7/21/2016

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BY: JEANETTE MUMFORD, CYRIL PERNET, THOMAS YEO, LISA NICKERSON, NILS MUHLERT, NIKOLA STIKOV, RANDY GOLLUB, & OHBM COMMUNICATIONS COMMITTEE (IN CONSULTATION WITH THOMAS NICHOLS)  

In recent weeks a lot of attention has been given to the paper “Cluster failure: Why fMRI inferences for spatial extent have inflated false-positive rates”, by Eklund, Nichols and Knutsson, in the Proceedings of the National Academy of Sciences.  This work highlights an important concern; however, some of the media attention has been based on a misunderstanding and an ‘inflated’ interpretation of the results.  Specifically, too much weight has been given to the numbers “40,000 impacted studies” and “70% false positives”, an unfortunate side effect of reducing a study rich in information to a few soundbites.  We respect the views of this paper and the effort put forth by the authors who, like the leadership of OHBM, understand there is a growing concern for validity and reproducibility in our field. The purpose of this post is to put these numbers in context and clarify how these findings impact our view of past and future fMRI results.

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#OHBM2016 IN REVIEW

7/9/2016

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BY CYRIL PERNET

​During the annual OHBM meeting in Geneva I had fun making word clouds from the twitter feed of the hashtag #OHBM2016. Attendants could see the word clouds in between every presentation, and I think it made the welcome screen look pretty cool (you can find them on the @OHBM_members channel and on the OHBM facebook page). In case you thought some information was missing, that is simply because it was either not that frequently discussed on Twitter or http://www.wordclouds.com/ did not show it (not all words appear depending on design and size). There was no censoring, and you can blame me if something was not to your liking.

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